for health technology assessment
From scoping review to systematic review, same platform.
PRISMA-ScR for the landscape map, PRISMA 2020 for the evidence base. AMSTAR 2 on the included systematic reviews; RoB 2 on the RCTs; QUADAS-2 on the diagnostic studies. The methodological apparatus your assessment requires, automated.
The HTA workflow before audit-grade AI
- Scoping the literature on a new technology takes weeks of database queries, screening, and charting — every assessment starts over from scratch.
- Risk-of-bias appraisal is mechanical work — RoB 2 on every RCT, AMSTAR 2 on every cited SR, QUADAS-2 on every diagnostic study — and gets cut for time on tight timelines.
- Living evidence syntheses (NICE-style continuous evidence reviews) are operationally hard. Most teams produce a static SR once, then watch it become stale.
- Justifying why a paper was included or excluded becomes painful when the search log isn't structured.
What Embarke gives an HTA team
Scoping review (PRISMA-ScR) + systematic review (PRISMA 2020) in one platform
Start with a PRISMA-ScR scoping review to map the breadth of the literature (Tricco et al., Ann Intern Med 2018). When you find the specific evidence question worth a deeper dive, run a PRISMA 2020 systematic review on the same project's saved framework. Both share the same source pool + extraction + citation infrastructure.
Risk-of-bias automation, not deferral
RoB 2, ROBINS-I, AMSTAR 2, QUADAS-2 — Embarke runs the appropriate tool per cited paper based on study design. Per-domain judgments are LLM-proposed with a rationale citing the source; the rollup to overall judgment is algorithmic (published rules), not LLM-guessed. Reviewers override any per-domain call inline.
Living synthesis for continuous-evidence workflows
Subscribe a project to scheduled re-runs (daily / weekly / monthly). Each fire produces a LivingDelta showing added citations, removed citations, and retraction-status changes on previously cited papers. The HTA team sees the evidence base move without manual database checks.
Source-tier enforcement matches HTA norms
Framework declares minimum source tier; PRISMA-aligned frameworks enforce tier B (peer-reviewed, preprint, regulatory, primary-interview only). Press releases, social media, generic blogs don't appear in the corpus. Same audit-trail logic the rest of HTA already runs on, codified.
A typical HTA workflow
Question lands → run a PRISMA-ScR scoping review (~5 minutes, ~30 sources) to map what's out there → identify the specific intervention-outcome question worth a full review → run a PRISMA 2020 systematic review on that question → AMSTAR 2 / RoB 2 / QUADAS-2 fire automatically per cited paper → export the methodology-stamped PDF for your assessment dossier → subscribe the project to weekly living-synthesis re-runs so the evidence base stays current through the assessment lifecycle.
Start a scoping review free
Free tier — three syntheses, no credit card. BYOK for the LLM so your costs stay on your account.